ACT — Nicotiana attenuata

Summary

A4A49_00747 (ACT) on coyote tobacco chromosome 10 encodes a protein with an actin/actin-like conserved sequence and ATPase NBD domain. The product exhibits profilin, phospholipid, actin, F-actin, protein kinase, and phosphorylated amino acid binding, plus structural constituent of cytoskeleton, phosphatase, hydrolase, transglycosidase, and copper binding activities. It localizes to the actin cytoskeleton, Golgi membrane, endosome, chloroplast envelope, and protein serine/threonine phosphatase and Cul4-RING E3 ubiquitin ligase complexes. The gene is associated with actin filament-based processes including nucleation, stabilization, depolymerization, capping, and gel formation, as well as cell tip growth, pronuclear migration, karyogamy, Golgi-to-plasma membrane transport, and response to nutrient. Associations with agronomic traits include seed morphology and yield, leaf area, vegetative vigor, water stress response, nitrogen and potassium sensitivity, aphid response, powdery mildew disease response, root hair length, shoot branching, and cell cycle traits.