PR-1 — Nicotiana attenuata

Summary

A4A49_01387 (PR-1) on chromosome 11 of coyote tobacco (Nicotiana attenuata) encodes a member of the CAP (cysteine-rich secretory protein) superfamily, containing a V5 allergen-like domain and a CRISP-related domain. The gene is associated with defense responses, including systemic acquired resistance, induced systemic resistance, innate immunity, and defense against other organisms. It is linked to salicylic acid and jasmonic acid anabolism, programmed cell death, leaf senescence, abscission, and virus-induced PTGS. The encoded protein localizes to the vacuole and extracellular space. PR-1 is associated with traits including chlorophyll a and b content, carbohydrate content, and lignin content, as well as phenotypes such as disease resistance, nematode resistance, and increased osmotic stress response. Studies of related genes in other species link the family to pathogen resistance, late blight resistance, and herbivore resistance.