TPI — Nicotiana attenuata

Summary

A4A49_01828 (symbol TPI, preferred name CTIMC) in coyote tobacco (Nicotiana attenuata) on chromosome 2 encodes a triose-phosphate isomerase with copper-binding activity. This gene is associated with glycolytic and gluconeogenic processes, the Calvin cycle, glyceraldehyde-3-phosphate anabolism, glycerol breakdown, and the reductive pentose-phosphate pathway. It has been linked to egg deposition, oviposition, chewing, memory, nonsense-mediated mRNA decay, ethylene anabolism, secondary metabolism, secretion, virus-induced PTGS, metabolic burst, and response to zinc. Localisation evidence links the product to the apoplast, cell wall, chloroplast stroma, vacuole, plasmodesmata, mitochondria, cytosol, and plasma membrane. The gene is associated with protein content and photosynthetic rate, as well as autophagy regulation and nectar protein accumulation. Studies of related genes in other species connect the family to herbivore defense, male fertility, and carbon and sugar metabolism.