AGR — Nicotiana attenuata

Summary

A4A49_02382 (AGR, PIN3) on chromosome 12 of Nicotiana attenuata encodes an auxin efflux carrier of the PIN family, possessing auxin efflux transmembrane transporter activity, inositol-1,4-bisphosphate 1-phosphatase activity, and phosphatidylinositol phosphate binding. The gene is associated with tropism, detection of oxidative stress, and response to brefeldin A. It is linked to traits including shoot growth angle, leaf vein morphology, seed set percent, root phototropism, blue light sensitivity, and auxin content. Associations extend to primary root growth, lateral root organogenesis, shoot apical dominance, pollen tube growth, and vascular development. The gene is connected to auxin signalling, clathrin-mediated endocytosis, and regulation of seed size pathways. Related genes in other species link the family to phototropic hypocotyl bending, gravitropism, fruit development, and leaf flattening.