NTF6 — Nicotiana attenuata

Summary

A4A49_02839 (NTF6) on chromosome 12 of coyote tobacco (Nicotiana attenuata) encodes a mitogen-activated protein kinase (MAPK) with serine/threonine and tyrosine kinase activity (EC 2.7.11.24). The gene is associated with cell cycle processes including mitosis, meiosis, anaphase, telophase, cytokinesis, and syngamy, as well as intracellular signal transduction, regulation of gene expression, and responses to wounding, UV-C, and innate immunity. It is linked to jasmonic acid and abscisic acid signaling, flavonoid biosynthesis, virus-induced post-transcriptional gene silencing, and lateral root formation. The encoded protein localizes to the cytoplasm and nucleus. Associations with stomatal aperture, drought response, reactive oxygen species production, flowering time, and resistance to Phytophthora infestans have been noted. Related genes in other species are linked to drought and salt stress tolerance, potassium and sodium uptake, fruit ripening, and pathogen resistance.