FLS2 — Nicotiana attenuata

Summary

A4A49_65968 (FLS2) in coyote tobacco (Nicotiana attenuata) encodes a leucine-rich repeat receptor-like kinase (LRR-RLK) with protein serine/threonine kinase activity, ATP binding, signaling receptor activity, and steroid, SNARE, and receptor serine/threonine kinase binding capabilities. It is associated with detection of brassinosteroid stimulus, activation of defense response to bacteria, upregulation of defense response, endocytosis, membrane fission, viral translation, virus-induced post-transcriptional gene silencing, and regulation of floral meristem size, floral organ development, anther wall tapetum development, microsporogenesis, megasporogenesis, gametophyte development, skotomorphogenesis, microtubule bundling, and cell growth. The protein localizes to the plasma membrane, ER membrane, perinuclear ER membrane, cortical ER, endosome, and nucleus. Studies of related genes in other species link the family to brassinosteroid perception, systemic defense signaling, and disease resistance.