PP2A — Nicotiana attenuata

Summary

A4A49_64719 (PP2A) in coyote tobacco (Nicotiana attenuata) encodes a protein with a PPA2-like domain, a Ser/Thr-specific protein phosphatase domain, a calcineurin-like phosphoesterase domain, and a metallo-dependent phosphatase-like domain, classified as EC 3.1.3.16. It is annotated with protein phosphatase regulator activity, protein tyrosine phosphatase activator activity, and cis-trans proline isomerase activity. The gene is associated with brassinosteroid signaling, TOR signaling, chloroplast avoidance movement, and regulation of abscisic acid anabolism. It has been linked to traits including biomass yield, seed yield, leaf elongation rate, root hair length, nitrate transport, cadmium concentration, and high temperature stress response. The protein localizes to the PP2A complex, cytosol, nucleus, and ER membrane. Studies of related genes in other species connect PP2A to phosphorus deficiency tolerance, ethylene signal transduction, iron acquisition, and salinity tolerance.