M2 — Nicotiana attenuata

Summary

A4A49_22112, designated NaM2 in coyote tobacco (Nicotiana attenuata) on scaffold00112, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) with cyclosporin A binding and cis-trans proline isomerase activity. The gene is associated with nicotine metabolism, the methylerythritol phosphate (MEP) pathway, isoprenoid anabolism, demethylation, detoxification, and secondary metabolism. It is linked to protein folding, regulation of protein refolding, signal transduction, excretion, and responses to abscisic acid, salt, and mannitol. Localisation evidence links the product to the chloroplast stroma, cytosol, cytoplasm, nucleus, and plasmalemma. Associations with leaf length, root length, protein content, and salt tolerance have been noted.