PIP — Nicotiana attenuata

Summary

A4A49_12388 (PIP, also known as NaPAP1 or NaPIP) on chromosome 3 of coyote tobacco (Nicotiana attenuata) encodes a proline iminopeptidase (EC 3.4.11.5) with aminopeptidase activity, belonging to the peptidase S33 and AB hydrolase families. The gene is associated with the biosynthesis of anthocyanins, flavonoids, phenylpropanoids, alkaloids, and polyamines, as well as with detoxification, proteolysis, response to salt and metals, ABA signaling, leaf development, and cell growth. It has been linked to photosynthetic rate, chlorophyll content, stomatal resistance, and turgor pressure. The protein localizes to the cytosol, cytoplasm, mitochondria, and secretory vesicles. Studies of related genes in other species connect the family to water transport, root hydraulic conductance, and reduced pollen viability with delayed post-stress growth.