LSU — Nicotiana attenuata

Summary

A4A49_13010 (LSU, also known as GGPS1) in coyote tobacco (Nicotiana attenuata) encodes a prenyl diphosphate synthase with all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity, farnesyltranstransferase activity, dimethylallyltransferase activity, FGPP synthase activity, geranyltranstransferase activity, prenyltransferase activity, transferase activity, and metal binding. The gene is associated with the biosynthesis of geranylgeranyl diphosphate, farnesyl diphosphate, geranyl diphosphate, and downstream isoprenoids including carotenoids, plastoquinone, ubiquinone, and terpenoids. It is linked to responses to herbivores, insects, jasmonic acid, salicylate, and blue light, as well as pigmentation, protein synthesis, and virus-induced PTGS. The encoded protein localizes to plastids, chloroplast thylakoid membranes, etioplasts, mitochondria, and the endoplasmic reticulum. Related genes in other species are linked to carotenoid biosynthesis and sesterterpene production.