FLS — Nicotiana attenuata

Summary

A4A49_13067 (FLS) in Nicotiana attenuata encodes a flavonol synthase, a 2-oxoglutarate-dependent dioxygenase with leucocyanidin oxygenase, flavanone 3-dioxygenase, and dihydroflavanol 4-reductase activities. It is associated with flavonol biosynthesis, proanthocyanidin and anthocyanin metabolism, pigmentation, and responses to UV-B light and gravity. The gene has been linked to flower color, seed size and maturation, photosynthetic rate, stomatal closure, root hair length, and tolerance to salt, drought, low temperature, and nitrogen stress. It is also associated with auxin biosynthesis and polar transport, endocytosis, and post-transcriptional gene silencing. Studies of related genes in other species link the family to flavonol synthesis, seed coat pigmentation, root gravitropism, and defense against cyst nematodes and bacterial pathogens.