AGR — Nicotiana attenuata

Summary

A4A49_13310 (AGR, also known as PIN8) on chromosome 2 of coyote tobacco (Nicotiana attenuata) encodes a member of the auxin efflux carrier family, possessing auxin efflux transmembrane transporter activity and inositol-1,4-bisphosphate 1-phosphatase activity. The gene is associated with auxin efflux transport, root gravitropism, and responses to abiotic stimuli. It has been linked to numerous traits including gravity response, phototropism, blue light sensitivity, auxin content, seed set percent, leaf vein morphology, shoot growth angle, stamen morphology, and root hair length. Associations also include regulation of endocytosis, phosphoinositide-mediated signaling, anthocyanin accumulation in response to UV light, and cellular response to basic pH. The encoded protein localizes to the auxin efflux carrier complex, recycling endosome, and basal plasma membrane. Studies of related genes in other species connect the family to fruit development, shoot architecture, and insect resistance.