AIK1 — Nicotiana attenuata

Summary

A4A49_14402 (AIK1, also known as NPK1) in Nicotiana attenuata encodes a protein kinase with MAPKKK activity, belonging to the plant MAPKKK family and possessing serine/threonine kinase and ATP-binding domains. It is associated with ABC-type transporter activities, including auxin efflux and cadmium ion transmembrane transport, and with diverse biological processes such as cytokinesis, lateral growth, indole glucosinolate breakdown, and regulation of defense response by callose deposition. The gene has been linked to traits including auxin content and sensitivity, jasmonic acid content, leaf senescence, root morphology, flowering time, and disease tolerance. Phenotypic associations include herbivore resistance, salt and osmotic stress tolerance, abscisic acid sensitivity, stomatal response, and seed germination. Studies of related genes in other species connect the family to drought resistance, plant immunity, and root growth.