MATE — Nicotiana attenuata

Summary

A4A49_11811, designated DTX42 (also known as MATE or NaMATE) in Nicotiana attenuata on chromosome 1, encodes a member of the MATE family, containing a DinF-like domain. The protein exhibits citrate transmembrane transporter, xenobiotic transmembrane transporter, and antiporter activities. This gene is associated with citrate transport, vacuolar transport, pH reduction, nicotine anabolism, and response to aluminum. It is linked to membrane and plasmalemma localization, particularly in root hairs, and to pathways involving efflux of citrate and responses to aluminum stress and heavy metals. Studies of related genes in other species connect the MATE family to aluminum tolerance and resistance, drought tolerance, root morphology traits, anthocyanin content, and fusarium head blight and wilt resistance.