PMIT1 — Lactuca sativa

Summary

LsPMIT1, a gene on lettuce chromosome 4, encodes a member of the NRAMP family of metal ion transporters, with molecular functions including manganese, iron, and cadmium transmembrane transporter activity. The gene is associated with the transport and homeostasis of several metal ions, particularly manganese and iron, and is linked to responses to manganese starvation and cadmium stress. LsPMIT1 has been connected to traits such as photosynthetic rate, root length, and plant height, as well as phenotypes including growth under manganese deficiency, copper homeostasis, and seed iron accumulation. The protein localises to the tonoplast, trans-Golgi network, endosome, and vacuolar membranes. Related genes in other species are linked to additional processes including pathogen resistance, oxidative stress tolerance, and photosystem II function.