BET9 — Lactuca sativa

Summary

LsBET9, encoded by gene LSAT_V11C400228020 on lettuce chromosome 4, is a bromodomain-containing protein with histone acetylase activity, sequence-specific DNA binding, and transcription coactivator activity. It is associated with numerous biological processes including regulation of nitrate assimilation, salicylic acid metabolism, antiviral responses, and shoot regeneration. The gene has been linked to traits such as seed protein content, seed dormancy, flowering time, whole plant size, root morphology, anthocyanin content, and responses to abiotic stresses including high and low temperature, oxidative stress, and salinity. It is also associated with disease tolerance and with cellular processes like cell cycle regulation, ploidy level, and DNA demethylation. Studies of related genes in other species link the family to telomerase activity, nitrogen assimilation, and responses to ABA, sucrose, and nitrate.