MS1 — Lactuca sativa

Summary

LsMS1 (MS1) on lettuce chromosome 5 encodes a protein with cobalamin-independent methionine synthase activity, as well as ADP-glucose pyrophosphatase, ADP-ribose pyrophosphatase, and NAD+ diphosphatase activities. It is associated with de novo L-methionine biosynthesis, regulation of starch biosynthesis, DNA methylation-dependent heterochromatin assembly, and responses to ozone, oxidative stress, bacteria, insects, and hypoxia. The gene is linked to whole plant size, seed development, root morphology, salt tolerance, and disease tolerance. Associations include male sterility, pollen exine development, and anther development. Related genes in other species connect the family to methionine levels, seed germination, oxidative stress tolerance, immunity, pathogen defense, callose deposition, and indolic glucosinolate biosynthesis.