TCP — Lactuca sativa

Summary

LsTCP, encoded by gene LSAT_V11C400216470 on lettuce chromosome 4, is a chaperonin belonging to the TCP-1 family with ATP-dependent protein folding chaperone activity and ATP binding. The gene is associated with protein folding and refolding, protein-peroxisome targeting, leaf development, cell division, and response to zinc. It localises to the cytosol, nucleus, plastid, mitochondria, and the TriC complex. Lettuce-specific associations link LsTCP to leaf shape and size, selenium and sulfur content, and peroxisome function including PTS2 protein import. Related genes in other species are linked to glyoxysomal function, cadmium tolerance, and PTS1 protein import into peroxisomes, and to traits including leaf length, seed weight, fruit weight and shape, chlorophyll content, and auxin and cytokinin levels.

Annotations

Chromosome
4
Related genes
TCP, PEX7, CCT6-1, CCT6-2
GO terms
GO:0005053, ATPase Binding, Cul4-RING E3 Ubiquitin Ligase Complex, Protein Refolding, response to zinc, ATP-dependent Protein Folding Chaperone, GO:0051082, Protein Folding
Publications
14577373, 30825377, 20736450, 16336779, 11378467, 28627464, PMID:30833711, 17432890
Traits
other miscellaneous trait, Reduced Peroxisomal Defects, Reduced Sensitivity to IBA, Fewer Lateral Roots, Se82, clim-pet1, clim-pet12, peroxisome function, glyoxysomal function, S34