SHD — Lactuca sativa

Summary

LsSHD, on lettuce chromosome 2, encodes a member of the heat shock protein 90 (Hsp90) family, containing Hsp90 and HATPase domains, and is annotated with ATP-dependent protein folding chaperone activity. The gene is associated with a wide range of biological processes, including cellular response to unfolded protein, cellular thermotolerance, response to brassinosteroid stimulus, and photoentrainment of the circadian clock. It is linked to traits such as floral organ morphology, seed set percent, reproductive growth time, and responses to bacterial, viral, and downy mildew diseases, as well as to submergence tolerance, temperature stress, and aphid response. Localisation evidence connects the product to the chloroplast outer membrane, ER lumen, and cell periphery. Studies of related genes in other species link the Hsp90 family to thermotolerance, broad-spectrum disease resistance, and salinity tolerance.