HORVU.MOREX.R3.5HG0516940 — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.5HG0516940, designated AXR6 and also known as CUL4, encodes a cullin-family scaffold protein that provides ubiquitin ligase complex scaffold activity and NEDD8 transferase activity on barley chromosome 5H. The gene is associated with grain morphology traits and has been linked to diverse biological processes including regulation of ethylene biosynthesis, protein neddylation, response to organophosphorus compounds, and regulation of gibberellic acid-mediated signalling. It is associated with auxin receptor activity, auxin binding, and protein neddylation. Associations extend to traits such as stem width, Cercospora leaf spot response, bacterial blight disease resistance, photoperiod sensitivity, and various mineral content traits including iron, sulfur, and molybdenum. Studies of related genes in other species link the family to drought stress, lesion mimic phenotypes, and disease resistance responses.