MEP1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoMEP1 (FOXG_16870) on chromosome 13 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a metallopeptidase belonging to the Peptidase_M43 family and the metallopeptidase catalytic domain superfamily. The gene product exhibits metallopeptidase activity and metal binding, and is annotated as a cytoplasmic effector localised to the extracellular space. It is associated with proteolysis and with evasion of symbiont recognition by the host pattern recognition receptor. Studies of related genes in other species link the family to reduced virulence, and the encoded protein is classified as an apoplastic effector.