ARF — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G18359 (ARF) on chromosome 3 of Fusarium graminearum PH-1 encodes a small GTPase of the Arl8a/8b and ARF/SAR families, with GTPase activity, GTP binding, and G protein activity, and is annotated as a protein membrane adaptor. The gene is associated with diverse biological processes including vesicle organization, ER-to-Golgi transport, nuclear envelope and mitochondrial membrane organization, mitochondrial fission, cell growth mode switching, regulation of mitotic cytokinesis, positive regulation of mitotic entry, innate immunity, and cellular response to AOS. It localizes to the mitochondria-associated membrane, COPII vesicle coat, ER exit site, Golgi membrane, division septum, cell cortex, and cell division site. Related genes in other species include ADP-ribosylation factor family proteins linked to small GTPase-mediated membrane trafficking.