FAS5 — Daucus carota subsp. sativus

Summary

DCAR_025937 (DcFAS5) on carrot chromosome 7 encodes a type I topoisomerase, a DNA-breaking and rejoining enzyme with chromatin, histone, and DNA-binding activities. The gene is associated with DNA topological change, replication, and chromatin modelling, as well as shoot and flower morphogenesis, meristem size regulation, stem cell maintenance, somatic embryogenesis, and plant organ formation. It has been linked to ascorbate metabolism, responses to UV and UV-A/UV-C, apoptotic processes, and autophagy. Associations with agronomic traits include nitrate uptake, leaf composition, seedling growth, flowering time, and abiotic stress responses, particularly salt tolerance. The gene is also connected to stem fasciation, phyllotaxis, plant architecture, and pathogen defence. Studies of related genes in other species link the family to inflorescence fasciation, meristem size, floral organ number, leaf morphology, and stress tolerance.