PRP8 — Daucus carota subsp. sativus

Summary

DCAR_022311 (DcPRP8) on carrot chromosome 6 encodes a protein with Prp8_U5-snRNA-bd, RRM_spliceosomal_PrP8, and other domains, and exhibits activities such as pre-mRNA intron binding, U1–U6 snRNA binding, protein methylase activity, metallopeptidase activity, and ubiquitin ligase activity. The gene is associated with spliceosome assembly, mRNA splicing, miRNA metabolism, cellulose microfibril organization, and regulation of circadian rhythm. In carrot, DcPRP8 is linked to sucrose and soluble sugar content. It is also associated with traits including yield, flowering time, seed longevity, bacterial blight disease resistance, boron sensitivity, nitrate uptake, heat and cold stress responses, and root and embryo development. The protein localizes to spliceosomal complexes, U5 snRNP, nuclear speck, and the ESCRT III complex.