GAPB — Daucus carota subsp. sativus

Summary

DCAR_022989 (symbol GAPB, also known as DcGAPDH) on carrot chromosome 6 encodes a glyceraldehyde-3-phosphate dehydrogenase with NADP+ and NAD+ phosphorylating activities, and is associated with additional molecular functions including histone acetyltransferase activity and binding to NAD, NADP, salicylic acid, chitin, and chitosan. The gene is associated with the reductive pentose-phosphate cycle, glucose metabolism, and plastid glycolysis, and its product localises to the chloroplast stroma, thylakoid membrane, envelope, stromule, apoplast, plasmodesma, cytosol, and plasmalemma. Associations include photosynthetic rate and efficiency, stomatal closure and immunity, osmotic and salinity tolerance, bacterial and fungal disease resistance, chitin signaling and immunity, brassinosteroid sensitivity, leaf vascular pattern formation, lateral root development, DNA methylation and demethylation, and gene silencing. Studies of related genes in other species link the family to chloroplast glyceraldehyde-3-phosphate dehydrogenase expression, defense responses, and thermotolerance.