PI3K — Daucus carota subsp. sativus

Summary

DCAR_018086, designated DcPI3K on carrot chromosome 5, encodes a phosphatidylinositol 3-kinase of the VPS34 class III type, possessing protein serine/threonine kinase activity and ATP binding. The gene is associated with phosphatidylinositol 3-phosphate biosynthesis, macroautophagy, pexophagy, TOR signaling, endocytosis, and phosphoinositide-mediated signaling. It is linked to apoptotic processes, regulation of stomatal closure, response to salt stress, and activation of defence response to bacteria. Associations with leaf senescence, pollen germination, root hair growth, proline accumulation, ethylene biosynthesis, and heat stress recovery have been observed. The encoded protein localises to endosome and Golgi membranes, the PAS, and class III PI3K and TOR complexes. Studies of related genes in other species link the family to plant growth and development, stomatal closure, disease resistance, and flower senescence.