M2 — Cucumis melo

Summary

MELO3C025848.2, designated CmM2 on melon chromosome 12, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase; EC 5.2.1.8) with cis-trans proline isomerase activity and cyclosporin A binding capacity. This protein localises to the chloroplast stroma, cytosol, nucleus and plasmalemma. It is associated with protein folding and the regulation of protein refolding, and is linked to fruit development and fruit ripening. The gene is associated with responses to abscisic acid, salt, and mannitol, and with activation of the salinity response. Related genes in other species link the cyclophilin family to stress tolerance and developmental processes.