M2 — Cucumis melo

Summary

MELO3C025868.2, designated CmM2 on melon chromosome 12, encodes a cyclophilin-family protein with a cyclophilin-like domain and cis-trans proline isomerase activity, also annotated for cyclosporin A binding. The gene is associated with protein folding and the regulation of protein refolding, as well as fruit development and fruit ripening. Its product has been localized to the chloroplast thylakoid lumen, chloroplast stroma, cytosol, plasmalemma, and cytoplasm. Studies of related genes in other species link the family to peptidyl-prolyl cis-trans isomerase activity (EC 5.2.1.8).