HMG1 — Cucumis melo

Summary

MELO3C026512.2, designated CmHMG1 on melon chromosome 4, encodes a hydroxymethylglutaryl-CoA reductase (NADPH) (EC 1.1.1.34). The gene is associated with the mevalonate pathway, sterol anabolism, triterpenoid anabolism, isoprenoid anabolism, saponin anabolism, and CoA metabolism. It is linked to fruit ripening, fruit size, photosynthetic rate, plant height, biomass, flowering time, male fertility, flower morphology and color, senescence, and responses to jasmonic acid, absence of light, wounding and pathogens. The product localises to the endoplasmic reticulum, plastid, peroxisome, mitochondrial and chloroplast membranes. Studies of related genes in other species link the family to mevalonate pathway regulation, isoprenoid biosynthesis and phytosterol content, fruit development, and steroidal glycoalkaloid content.