NSF — Cucumis melo

Summary

MELO3C026279.2, designated CmNSF, encodes a member of the AAA+ ATPase family, specifically a CDC48-type ATPase with domains including AAA_ATPase_CDC48 and AAA_lid_3. The encoded protein exhibits multiple molecular functions, including ATPase binding, polyubiquitin modification-dependent protein binding, and proteasomal ATPase activity. CmNSF is associated with a wide range of biological processes, including protein complex disassembly, membrane fusion, organ growth, pollen maturation, meristem organization, and response to freezing. It has been linked to traits such as plant male sterility, seed longevity, flowering time, disease tolerance, and herbicide sensitivity. Localization evidence connects the protein to the p97-Ufd1-Npl4 complex, nuclear envelope, cell plate, and spindle. Studies of related genes in other species link the family to cell division, cytokinesis, seed development, and antiviral resistance.