RAD — Camelina sativa

Summary

CSA17G002380, also known as RAD or CsGEN1, encodes a protein with flap endonuclease activity, 5'-3' exonuclease activity, endodeoxyribonuclease RUS activity, ssDNA binding, dsDNA binding, Mg binding, metal binding, DNA binding, and protein binding, containing XPG/Rad2 and PIN-like domains. In Camelina sativa, this gene is associated with DNA repair, Okazaki initiator RNA removal, cell cycle G2/M phase transition, telomere maintenance, UV protection, DNA metabolism, positive regulation of stomatal complex development, guard mother cell differentiation, lateral root formation, pollen development, regulation of mitotic entry, DNA re-duplication, and BER. The protein localizes to the nucleus, nucleolus, and mitochondria. Associations with drought tolerance, cell cycle progression, endoreduplication, ploidy level, and stomatal development have been noted. Related genes in other species are linked to cell differentiation.