HPR3 — Camelina sativa

Summary

CsHPR3 (CSA17G016760) on Camelina sativa chromosome 17 encodes a protein with multiple NAD(P)H-dependent oxidoreductase activities, including formate dehydrogenase, (2R)-hydroxyphenylpyruvate reductase, glycerate dehydrogenase, glyoxylate reductase, hydroxypyruvate reductase, and D-lactate dehydrogenase activities. The protein contains a D-isomer-specific 2-hydroxyacid dehydrogenase catalytic domain and NAD(P)-binding domain. CsHPR3 is associated with the oxidative photosynthetic carbon pathway, formate breakdown, immune response, hypersensitivity, and homeostasis. It localizes to mitochondria and cytosol. The gene is linked to photorespiratory flux, photochemical efficiency, and plant growth. Studies of related genes in other species link the family to 4-hydroxyphenyllactic acid accumulation and impaired tyrosine conversion, as well as general plant growth and development traits.