PPAR — Camelina sativa

Summary

CSA17G016770 (symbol PPAR) on Camelina sativa chromosome 17 encodes a protein with D-isomer-specific 2-hydroxyacid dehydrogenase catalytic and NAD(P)-binding domains. The gene product has been annotated with multiple oxidoreductase activities, including formate dehydrogenase (NAD+), hydroxypyruvate reductase [NAD(P)H], glyoxylate reductase (NADH/NADPH), glycerate dehydrogenase (NAD+), and D-lactate dehydrogenase (NAD+) activities. It is associated with photorespiration, the oxidative photosynthetic carbon pathway, formate breakdown, hypersensitivity, immune response, and homeostasis. The protein localises to mitochondria and cytosol. Studies of related genes in other species link the family to hydroxypyruvate reductase (EC 1.1.1.237), glycerate dehydrogenase (EC 1.1.1.29), and formate dehydrogenase (EC 1.17.1.9) activities.