HSP70 — Camelina sativa

Summary

CSA17537S010 (HSP70) in Camelina sativa encodes a member of the Hsp70 family of protein folding chaperones, possessing ATP hydrolase activity and heat shock protein binding capacity. The gene is associated with the endoplasmic reticulum unfolded protein response (erUPR), ERAD pathway, and protein refolding, as well as the MAPK cascade, signal transduction, and responses to heat, salt, virus, and general stress. It has also been connected to pollen tube growth. The encoded protein localises to the ER chaperone complex, ER lumen, chloroplast membrane, tonoplast, cytoplasm, and nucleus. Studies of related Hsp70 family members in other species, including BIP and HSC proteins, further link this family to protein folding and stress responses.