PAD3 — Camelina sativa

Summary

CsPAD3 (CSA03G055550) on chromosome 3 of Camelina sativa encodes a cytochrome P450 family 71 protein with dihydrocamalexic acid decarboxylase, costunolide synthase, and 4-hydroxyphenylacetaldehyde oxime monooxygenase activities. The gene is associated with camalexin and indole phytoalexin biosynthesis, sesquiterpene and terpenoid metabolism, and dhurrin production. It has been linked to defense responses against fungi, bacteria, and insects, including resistance to Leptosphaeria maculans, Alternaria brassicicola, downy mildew, powdery mildew, clubroot, and Phytophthora brassicae, as well as aphid resistance and the hypersensitive response. Additional associations include fruit ripening, response to abscisic acid, zinc stress tolerance, and regulation of systemic acquired resistance. The protein localizes to the endoplasmic reticulum membrane, plasmodesmata, and extracellular space.