GAD — Camelina sativa

Summary

CsGAD3 (CSA04G006420) on Camelina sativa chromosome 4 encodes a glutamate decarboxylase with pyridoxal phosphate and calmodulin binding activities, also annotated for sphinganine-1-phosphate aldolase activity. The gene is associated with glutamate and sphingolipid breakdown, carboxylic acid and secondary metabolism, detoxification, and nitric oxide storage. It localizes to the ER membrane, mitochondria, and cytosol. CsGAD3 is associated with root length, heat stress tolerance, high light and heat stress tolerance, E-2-hexenal response, and bacterial pathogen resistance. Studies of related genes in other species link the GAD family to hypoxia response and GABA-deficient phenotypes under heat and light stress, while sequence similarity connections associate the family with water use efficiency, stomatal resistance, and high temperature stress response.