HMA2 — Brassica oleracea

Summary

BoHMA2 (BOLC102_C01P009880.1) on cabbage chromosome 1 encodes a P-type ATPase of the IB subfamily, a cation-transporting pump with annotated activities including copper, zinc, cadmium and calcium transport, ATP hydrolysis and calmodulin binding. The gene is associated with detoxification of copper ions, copper and zinc ion homeostasis, proton export across the plasma membrane, and response to cold and toxic substances. It is linked to vacuolar, Golgi and plasma membranes. Associations with photosynthetic rate, chlorophyll content and root length have been noted, as well as with cadmium tolerance, translocation and accumulation, zinc partitioning and translocation, metal homeostasis, fungal resistance and cadmium sensitivity. Studies of related genes in other species connect the family to zinc homeostasis, cadmium xylem loading and long-distance cadmium translocation.