IRT1 — Brassica oleracea

Summary

BoIRT1 (BOLC102_C01P014850.1_BOLC102_V1) on cabbage chromosome 1 encodes a member of the ZIP family of metal transporters, possessing copper, iron, manganese, zinc and cadmium ion transmembrane transporter activities, along with phosphoinositide, ubiquitin and mRNA binding. The gene is associated with the transport of nickel, manganese, zinc and cadmium, as well as cellular and multicellular iron homeostasis, auxin anabolism, downregulation of abscisic acid signalling, response to hypoxia and bacteria, and signal transduction. It localises to the plasma membrane, endosome, late endosome membrane, TGN, ESCRT I complex and nucleus. BoIRT1 is associated with photosynthetic rate and efficiency, chlorophyll content, plant growth and development, root and leaf development, chloroplast development, metal homeostasis and accumulation (including iron, cadmium, zinc, gold and uranium), iron deficiency tolerance and response, disease resistance, salt tolerance, chromium stress response, and circadian period length. Related genes in other species are linked to iron uptake, acquisition, translocation and transport, as well as nickel, arsenic and copper accumulation, cadmium sensitivity, zinc tolerance, and vacuolar biogenesis.