IRT1 — Brassica oleracea

Summary

BoIRT1 (BOLC102_C01P014870.1) on cabbage chromosome 1 encodes a ZIP family protein with copper, iron, manganese, zinc, and cadmium ion transmembrane transporter activities, along with phosphoinositide, ubiquitin, mRNA, and protein binding. The gene is associated with nickel, manganese, zinc, and cadmium transport, cellular and multicellular iron homeostasis, auxin anabolism, downregulation of abscisic acid signaling, response to hypoxia and bacteria, and MVB formation. It localizes to the plasma membrane, endosome, late endosome membrane, TGN, ESCRT I complex, and nucleus. BoIRT1 is linked to photosynthetic rate and efficiency, chlorophyll content, plant growth and development, root and leaf development, metal homeostasis and accumulation (iron, cadmium, zinc, gold), iron deficiency tolerance, chromium stress response, disease resistance, and circadian period length. Related genes in other species are linked to iron uptake, transport, and translocation, nickel and arsenic accumulation, and cadmium sensitivity.