AGR — Brachypodium distachyon

Summary

BRADI_4G26300V3 (BdAGR) encodes a member of the PIN-like auxin efflux carrier family, possessing auxin efflux transmembrane transporter activity and inositol-1,4-bisphosphate 1-phosphatase activity, along with multiple phosphoinositide-binding capabilities. In Brachypodium distachyon, this gene is associated with auxin transport and signalling pathways, gravitropism, regulation of seed size, and reproductive structure development. It has been linked to diverse biological processes including tropism, endocytic recycling, response to oxidative stress and cation stress, regulation of cell polarization, and phragmoplast microtubule organization. The encoded protein localizes to the auxin efflux carrier complex, basal plasma membrane, recycling endosome, and clathrin-coated vesicles. Associations with traits such as gravity response, phototropism, root and shoot architecture, leaf morphology, seed set, and sensitivity to hormones, herbicides, and various stresses have been noted. Studies of related genes in other species connect the family to plant height, tillering, root system architecture, pollen development, and aluminium tolerance.