UBC13 — Brachypodium distachyon

Summary

BRADI_4G27897V3 (UBC13) encodes a ubiquitin-conjugating enzyme (E2) with ubiquitin ligase and ubiquitin-protein transferase activities, belonging to the UBC protein family. In Brachypodium distachyon, this gene is associated with protein K63-linked ubiquitination, cytokinin and auxin metabolism, and upregulation of abscisic acid-mediated signaling. It is linked to negative regulation of response to water deprivation, root epidermal cell differentiation, response to iron, DNA damage response, and proteasomal pathway. The protein localizes to the cytosol, nucleus, endoplasmic reticulum, mitochondria, and plasma membrane. Associations include abscisic acid sensitivity, salt stress tolerance, drought stress tolerance, seed germination, root hair development, and metal homeostasis. Related genes in other species link the family to broad-spectrum disease resistance and immunity, and to drought regulation.