SHD — Brachypodium distachyon

Summary

BdSHD (BRADI_4G32941V3) on chromosome 4 of Brachypodium distachyon encodes a member of the heat shock protein 90 (HSP90) family, containing Hsp90_N, Hsp90_fam, and HATPase domains, and is annotated as an ATP-dependent protein folding chaperone with CDP-glycerol diphosphatase and 2',3'-cyclic-nucleotide 2'-phosphodiesterase activities. The gene is associated with diverse biological processes including thylakoid membrane organization, chloroplast stroma protein import, de-etiolation, defense response to insects, and fatty acid beta-oxidation. It localizes to the chloroplast thylakoid, inner membrane, nucleoid, and ER lumen. BdSHD is linked to agronomically important traits such as flowering time, seed set, seed viability, pollen fertility, root development, high temperature stress response, bacterial disease response, and plant growth and development. Studies of related genes in other species connect the family to thermotolerance, disease resistance, plastid function, and thylakoid membrane homeostasis.