G2 — Brachypodium distachyon

Summary

BdG2 (BRADI_4G23035V3) on chromosome 4 of Brachypodium distachyon encodes a protein with domains including ACP_syn_III_C, 3-ktacl-CoA_syn, FAE1_typ3_polyketide_synth, and Thiolase-like, and is annotated with trihydroxybenzophenone synthase activity, tetrahydroxybenzophenone synthase activity, acetoacetyl-CoA reductase activity, trans-2-enoyl-CoA reductase (NADPH) activity, ketoreductase activity, 3-hydroxyacyl-CoA dehydratase activity, acyltransferase activity, and ELOVL activity, among others. The gene is associated with very-long-chain fatty acid and wax anabolism, suberin biosynthesis, cutin-based cuticle development, sphingolipid metabolism, pollen tube development, trichome branching and papilla formation, and responses to UV, cold, and osmotic stress. It has been linked to traits including drought tolerance, salt tolerance, disease tolerance, flowering time, male sterility, seed coat color, leaf vein morphology, root morphology, manganese sensitivity, abscisic acid sensitivity, and high temperature stress response. The encoded protein localises to the endoplasmic reticulum membrane and the fatty acid elongase complex. Studies of related genes in other species connect the family to cuticular wax deposition, root suberin biosynthesis, pollen fertility, and grain weight.