AN3 — Arabidopsis thaliana

Summary

AT5G28640 (AN3, also known as GIF1) encodes a protein containing an SS18_N domain and is associated with diverse molecular functions including fucosidase, beta-glucosidase, and glutathione transferase activities, as well as translation repressor and transcription corepressor activities. The gene is linked to the regulation of organ size, leaf cell size, and iron uptake in Arabidopsis. It has been connected to numerous biological processes such as embryonic meristem initiation, floral whorl morphogenesis, maintenance of seed dormancy, and glucosinolate breakdown. AN3 is localized to the SAGA complex, SWI-SNF complex, and nuclear lamina. The gene is associated with agronomically relevant traits including grain size, fruit yield, leaf width, stem thickness, plant organ growth, and responses to boron and copper sensitivity. Studies of related genes in other species link the family to fruit production and regeneration efficiency.