NDR1 — Arabidopsis thaliana

Summary

AT3G20600, designated NDR1 (non-race specific disease resistance 1) in Arabidopsis thaliana, encodes an uncharacterized protein belonging to the NDR1-like family. The product is associated with protein binding and is localized to the plasma membrane, plasmodesmata, cytosol, and nucleus. NDR1 is associated with pathogen defense, including effector-triggered immunity, hypersensitive response regulation, and induced systemic resistance. It is linked to jasmonic acid anabolism, auxin transport, stomatal closure, autophagic cell death, and UV protection. Phenotypic associations include impaired disease resistance, altered leaf and stem trichomes, dwarfism with leaf lesions, electrolyte leakage, and resistance to Rhizoctonia and Verticillium longisporum. The gene is also associated with traits like drought tolerance, flowering time, leaf senescence, proline content, and turgor pressure. Studies of related genes in tomato link the NDR1 family to susceptibility to bacterial pathogens and reduced hypersensitive response.