RB — Arabidopsis thaliana

Summary

AT3G12280, also known as RB, RBR1 or RETINOBLASTOMA-RELATED 1 in Arabidopsis thaliana, encodes a retinoblastoma-related protein containing RB_A, RB_B and RB_N domains and a cyclin-like superfamily domain. The product exhibits DNA-binding transcription activator and transcription factor activity, transcription corepressor binding, CDK activity, protein serine/threonine kinase activity, and protein dimerization activity. It is associated with G1 phase cell cycle arrest, mitotic exit, cell cycle checkpoints, and G1/S transition, as well as asymmetric stem cell division, stem cell renewal and differentiation, embryonic organogenesis, palisade mesophyll development, generative cell differentiation, and DNA imprinting. The protein localises to the microsporocyte and generative cell nuclei, spindle, and chromatin silencing and HDAC complexes. Associations with traits include seed size, dormancy, germination rate, leaf size and shape, root development, water use efficiency, photosynthetic rate, photoperiod sensitivity, and sucrose and oleic acid content.