SIS7 — Arabidopsis thaliana

Summary

AT3G14440, also known as SIS7, NCED3, and STO1 in Arabidopsis thaliana, encodes a 9-cis-epoxycarotenoid dioxygenase, an enzyme with 9-cis-epoxycarotenoid dioxygenase activity that belongs to the carotenoid oxygenase family and binds metal ions. This gene is associated with abscisic acid (ABA) biosynthesis and accumulation, particularly under drought and dehydration stress, and with drought tolerance and salt stress response. It is linked to stomatal closure and resistance, osmotic stress tolerance, and responses to boron toxicity and temperature extremes. Associations also include lateral root development, shoot branching, seed dormancy and germination rate, leaf senescence, chlorophyll content, and disease tolerance, including resistance to Botrytis cinerea. The encoded protein localises to the chloroplast thylakoid membrane and stroma, and is connected to pathways in ABA homeostasis, hormone signaling, and metabolism.