HSP70 — Arabidopsis thaliana

Summary

AT3G12580 (HSP70-4, also known as Hsc70-4) encodes a heat shock 70 kDa protein family member with ATP-dependent protein folding chaperone activity, DXP-synthase activity, and ATP-dependent peptidase activity. This Arabidopsis thaliana gene on chromosome 3 is associated with heat stress tolerance, protein denaturation, mitochondrial protein import, RuBisCO assembly, and the MEP pathway. It has been linked to numerous agronomically relevant traits including biomass yield, photosynthetic ability, water use efficiency, rubisco content, leaf chlorophyll content, carotenoid content, seed maturation, germination rate, and responses to high temperature, bacterial disease, and abiotic stress. The protein localizes to the mitochondrial outer membrane, chloroplast thylakoid, and stress granules. Studies of related genes in other species connect the family to disease resistance responses in wheat and tomato.