PAP1 — Arabidopsis thaliana

Summary

AT1G56650 (PAP1, also known as AtMYB75) encodes a MYB-domain transcription factor that binds DNA and has DNA-binding transcription factor activity, RNA polymerase II-specific. In Arabidopsis thaliana, PAP1 is associated with the regulation of anthocyanin and flavonoid metabolism, including both positive regulation of anthocyanin metabolism and negative regulation of anthocyanin anabolism. The gene is linked to nitrogen homeostasis, glyoxylate metabolism, flavonol metabolism, and sucrose-mediated signaling. Observed phenotypes include insect resistance and photobleaching tolerance. PAP1 localizes to the nucleus and is associated with ubiquitin ligase complexes, including the Cul4-RING E3 complex. The gene has been connected to numerous traits including seed color, seed shattering, root epidermal cell length, leaf trichome density, light sensitivity responses, submergence tolerance, plant height, and secondary cell wall deposition. Related genes in other species are linked to circadian rhythm regulation in yeast.