AS2 — Arabidopsis thaliana

Summary

AT1G65620 (AS2, ASYMMETRIC LEAVES 2) on Arabidopsis thaliana chromosome 1 encodes a LOB domain-containing protein with DNA-binding transcription factor activity, sequence-specific double-stranded DNA binding, and histone H3K27 trimethylase activity. AS2 is associated with adaxial/abaxial axis specification, leaf cell fate specification, organ boundary specification between lateral organs and the meristem, and proximodistal axis specification. The gene is linked to shoot apical meristem development, cotyledon morphogenesis, gynoecium and fruit patterning, and reproductive structure development. Associations include leaf flexibility, leaf angle, leaf margin serrated, leaf area, petal color and size, silique fruit morphology trait, seed shattering, harvest index, phosphorus and selenium content, brassinosteroid content, and root branching. The protein localizes to the nucleus, nucleolus, condensed chromosome, and chromatin silencing complex.